Senior Research Associate Gene Editing

Profile

Bristol-Myers Squibb is a global Biopharma company committed to a single mission: to discover, develop, and deliver innovative medicines focused on helping millions of patients around the world in disease areas such as oncology, cardiovascular, immunoscience and fibrosis.

Join us and make a difference. We hire the best people and provide them with a work environment that places a premium on diversity, integrity, collaboration and personal development. Through a culture of inclusion, we create a better, more productive work environment. We believe that the diverse experiences and perspectives of all our employees help to drive innovation and transformative business results.

Position

Senior Research Associate, Gene-editing technology

Job Description

The Cell Therapy Technology & Platforms group is seeking an enthusiastic individual to join the Gene Editing and process development team. The successful candidate will support autologous and allogeneic first-in-human cell therapy programs. He/she will be an integral part of the multidisciplinary CMC team to support IND enabling studies. The position will require experimental design, experimental execution, data analysis, drafting of technical reports, and presentation of results in the technical team meeting.

Education

A degree in biology, cell biology, microbiology, immunology, bio/chemical engineering or a related scientific field

Bachelors plus two or more years of relevant experience

Masters plus one more or years of relevant experience

Experience

Experience with T cell or primary cell or stem cells culture

Experience with genetic manipulation in mammalian cells using CRISPR-Cas9 or related technologies

Experience with developing and optimizing gene-editing reagent

Experience working with a larger group in a matrix environment

Experience with viral (Lentivirus and AAV) or non-viral gene delivery methods

Experience with nucleic acid (DNA and RNA) purification, PCR, ddPCR, Q-PCR, Sanger, and next-generation sequencing

Experience with flow cytometry or cell-based assays

Experience with writing technical documents for interdepartmental use

Duties and Responsibilities

Work with various scientists to support IND enabling studies

Work closely with process development scientists to support at scale gene-editing experiments

Perform various molecular as well as cell-based assays to support on-going studies

Work with external CMOs to support gene-editing reagent development activity

Work with external partners to evaluate new technology in cell therapy space

Write technical reports, including development reports and Standard Operating Procedures.

Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

Bristol-Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

Company info

Bristol-Myers Squibb Company
Website : http://www.bms.com